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Bioluminescent bioreporter integrated circuit devices and methods for detecting ammonia

United States Patent

April 24, 2007
View the Complete Patent at the US Patent & Trademark Office
Bioluminescent Bioreporter Integrated Circuits
Monolithic bioelectronic devices for the detection of ammonia includes a microorganism that metabolizes ammonia and which harbors a lux gene fused with a heterologous promoter gene stably incorporated into the chromosome of the microorganism and an Optical Application Specific Integrated Circuit (OASIC). The microorganism is generally a bacterium.
Simpson; Michael L. (Knoxville, TN), Paulus; Michael J. (Knoxville, TN), Sayler; Gary S. (Blaine, TN), Applegate; Bruce M. (West Lafayette, IN), Ripp; Steven A. (Knoxville, TN)
UT-Battelle LLC (Oakridge, TN)
11/ 152,139
June 14, 2005
The United States government has rights in the present invention pursuant to grant number DE-FG05-94ER61870 from the Department of Energy and grant number F49620-89-C-0023 from the United States Air Force.