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Device for two-dimensional gas-phase separation and characterization of ion mixtures

United States Patent

December 12, 2006
View the Complete Patent at the US Patent & Trademark Office
Pacific Northwest National Laboratory - Visit the Technology Commercialization Program Website
The present invention relates to a device for separation and characterization of gas-phase ions. The device incorporates an ion source, a field asymmetric waveform ion mobility spectrometry (FAIMS) analyzer, an ion mobility spectrometry (IMS) drift tube, and an ion detector. In one aspect of the invention, FAIMS operating voltages are electrically floated on top of the IMS drift voltage. In the other aspect, the FAIMS/IMS interface is implemented employing an electrodynamic ion funnel, including in particular an hourglass ion funnel. The present invention improves the efficiency (peak capacity) and sensitivity of gas-phase separations; the online FAIMS/IMS coupling creates a fundamentally novel two-dimensional gas-phase separation technology with high peak capacity, specificity, and exceptional throughput.
Tang; Keqi (Richland, WA), Shvartsburg; Alexandre A. (Richland, WA), Smith; Richard D. (Richland, WA)
Battelle Memorial Institute (Richland, WA)
11/ 103,984
April 11, 2005
STATEMENT OF GOVERNMENT SUPPORT This invention was made with United States Government support under Contract DE-AC05-76RL01830 awarded by the U.S. Department of Energy. The United States Government has certain rights in the invention.