Skip to Content
Find More Like This
Return to Search

Contrast enhancing solution for use in confocal microscopy

United States Patent

October 31, 2006
View the Complete Patent at the US Patent & Trademark Office
U.S. Department of Energy - Visit the Office of the Assistant General Counsel for Technology Transfer & Intellectual Property Website
A method of optically detecting a tumor during surgery. The method includes imaging at least one test point defined on the tumor using a first optical imaging system to provide a first tumor image. The method further includes excising a first predetermined layer of the tumor for forming an in-vivo defect area. A predetermined contrast enhancing solution is disposed on the in-vivo defect area, which is adapted to interact with at least one cell anomaly, such as basal cell carcinoma, located on the in-vivo defect area for optically enhancing the cell anomaly. Thereafter the defect area can be optically imaged to provide a clear and bright representation of the cell anomaly to aid a surgeon while surgically removing the cell anomaly.
Tannous; Zeina (Boston, MA), Torres; Abel (Loma Linda, CA), Gonzalez; Salvador (Newton, MA)
The United States of America as represented by the United States Department of Energy (Washington, DC), N/A (
10/ 607,630
June 27, 2003
STATEMENTS REGARDING FEDERALLY SPONSORED RESEARCH This invention was made with Government support under Grant No. DE-FG02-91ER61228 awarded by the U.S. Department of Energy. The Government may have certain rights to this invention.