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Thermal tolerant cellulase from Acidothermus cellulolyticus

United States Patent

7,059,993
June 13, 2006
View the Complete Patent at the US Patent & Trademark Office
National Renewable Energy Laboratory - Visit the NREL Technology Transfer Website
Cellulase Enzymes for the Conversion of Biomass to Biofuels and Chemicals
The invention provides a thermal tolerant cellulase that is a member of the glycoside hydrolase family. The invention further discloses this cellulase as GuxA. GuxA has been isolated and characterized from Acidothermus cellulolyticus. The invention further provides recombinant forms of the identified GuxA. Methods of making and using GuxA polypeptides, including fusions, variants, and derivatives, are also disclosed.
Ding; Shi-You (Golden, CO), Adney; William S. (Golden, CO), Vinzant; Todd B. (Golden, CO), Himmel; Michael E. (Littleton, CO), Decker; Stephen R. (Berthoud, CO)
Midwest Research Institute (Kansas City, MO)
09/ 917,383
20030104522
July 28, 2001
GOVERNMENT INTERESTS The United States Government has rights in this invention under Contract No. DE-AC36-99G010337 between the United States Department of Energy and the National Renewable Energy Laboratory, a Division of the Midwest Research Institute.