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In vivo incorporation of unnatural amino acids

United States Patent

7,045,337
May 16, 2006
View the Complete Patent at the US Patent & Trademark Office
Lawrence Berkeley National Laboratory - Visit the Technology Transfer and Intellectual Property Management Department Website
The invention provides methods and compositions for in vivo incorporation of unnatural amino acids. Also provided are compositions including proteins with unnatural amino acids.
Schultz; Peter (La Jolla, CA), Wang; Lei (San Diego, CA), Anderson; John Christopher (San Diego, CA), Chin; Jason William (San Diego, CA), Liu; David R. (Lexington, MA), Magliery; Thomas J. (North Haven, CT), Meggers; Eric L. (Philadelphia, PA), Mehl; Ryan A. (San Diego, CA), Pastrnak; Miro (San Diego, CA), Santoro; Steven William (San Diego, CA), Zhang; Zhiwen (San Diego, CA)
The Scripps Research Institute (La Jolla, CA), The Regents of the University of California (Oakland, CA)
10/ 126,927
April 19, 2002
STATEMENT REGARDING FEDERALLY SPONSORED RESEARCH AND DEVELOPMENT The invention was made with United States Government support under Contract No. ONR-6502573 from the Office of Naval Research, Contract No. NIH GM62159 from the National Institutes of Health, and Contract Nos. DE-FG03-00ER45812, DE-AC03-76SF00098 from the Department of Energy. The United States Government has certain rights in the invention.