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Method and apparatus for controlling cross contamination of microfluid channels

United States Patent

February 7, 2006
View the Complete Patent at the US Patent & Trademark Office
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A method for controlling fluid flow at junctions in microchannel systems. Control of fluid flow is accomplished generally by providing increased resistance to electric-field and pressure-driven flow in the form of regions of reduced effective cross-sectional area within the microchannels and proximate a channel junction. By controlling these flows in the region of a microchannel junction it is possible to eliminate sample dispersion and cross contamination and inject well-defined volumes of fluid from one channel to another.
Hasselbrink, Jr.; Ernest F. (Walnut Creek, CA), Rehm; Jason E. (Alameda, CA), Paul; Phillip H. (Livermore, CA), Arnold; Don W. (Livermore, CA)
Sandia National Laboratories (Livermore, CA)
09/ 669,862
September 26, 2000
STATEMENT OF GOVERNMENT INTEREST This invention was made with Government support under contract no. DE-AC04-94AL85000 awarded by the U.S. Department of Energy to Sandia Corporation. The Government has certain rights in the invention.