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Bioluminescent bioreporter integrated circuit detection methods

United States Patent

6,905,834
June 14, 2005
View the Complete Patent at the US Patent & Trademark Office
Bioluminescent Bioreporter Integrated Circuits
Disclosed are monolithic bioelectronic devices comprising a bioreporter and an OASIC. These bioluminescent bioreporter integrated circuit are useful in detecting substances such as pollutants, explosives, and heavy-metals residing in inhospitable areas such as groundwater, industrial process vessels, and battlefields. Also disclosed are methods and apparatus for detection of particular analytes, including ammonia and estrogen compounds.
Simpson; Michael L. (Knoxville, TN), Paulus; Michael J. (Knoxville, TN), Sayler; Gary S. (Knoxville, TN), Applegate; Bruce M. (Knoxville, TN), Ripp; Steven A. (Knoxville, TN)
UT-Battelle, LLC (Oak Ridge, TN)
09/ 660,581
September 12, 2000
The United States government has rights in the present invention pursuant to grant number DE-FG05-94ER61870 from the Department of Energy and grant number F49620-89-C-0023 from the United States Air Force.