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Influenza sensor

United States Patent

May 17, 2005
View the Complete Patent at the US Patent & Trademark Office
Los Alamos National Laboratory - Visit the Technology Transfer Division Website
A sensor for the detection of tetrameric multivalent neuraminidase within a sample is disclosed, where a positive detection indicates the presence of a target virus within the sample. Also disclosed is a trifunctional composition of matter including a trifunctional linker moiety with groups bonded thereto including (a) an alkyl chain adapted for attachment to a substrate, (b) a fluorescent moiety capable of generating a fluorescent signal, and (c) a recognition moiety having a spacer group of a defined length thereon, the recognition moiety capable of binding with tetrameric multivalent neuraminidase.
Swanson; Basil I. (Los Alamos, NM), Song; Xuedong (Los Alamos, NM), Unkefer; Clifford (Los Alamos, NM), Silks, III; Louis A. (Los Alamos, NM), Schmidt; Jurgen G. (Los Alamos, NM)
The Regents of the University of California (Los Alamos, NM)
10/ 651,141
August 28, 2003
This invention was made with government support under Contract No. W-7405-ENG-36 awarded by the U.S. Department of Energy. The government has certain rights in the invention.