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Solid-state detector and optical system for microchip analyzers

United States Patent

March 15, 2005
View the Complete Patent at the US Patent & Trademark Office
A miniaturized optical excitation and detector system is described for detecting fluorescently labeled analytes in electrophoretic microchips and microarrays. The system uses miniature integrated components, light collection, optical fluorescence filtering, and an amorphous a-Si:H detector for detection. The collection of light is accomplished with proximity gathering and/or a micro-lens system. Optical filtering is accomplished by integrated optical filters. Detection is accomplished utilizing a-Si:H detectors.
Mathies; Richard A. (Moraga, CA), Kamei; Toshihiro (Emeryville, CA), Scherer; James R. (Richmond, CA), Street; Robert A. (Palo Alto, CA)
The Regents of the University of California (Oakland, CA)
10/ 269,138
October 10, 2002
GOVERNMENT SUPPORT This invention was made with Government support under Grant No. FG03-91ER61125 awarded by the Department of Energy. The Government has certain rights to this invention.