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Purine inhibitors of protein kinases, G proteins and polymerases

United States Patent

October 12, 2004
View the Complete Patent at the US Patent & Trademark Office
Lawrence Berkeley National Laboratory - Visit the Technology Transfer and Intellectual Property Management Department Website
The present invention relates to 2-N-substituted 6-(4-methoxybenzylamino)-9-isopropylpurines that inhibit, inter alia, protein kinases, G-proteins and polymerases. In addition, the present invention relates to methods of using such 2-N-substituted 6-(4-methoxybenzylamino)-9-isopropylpurines to inhibit protein kinases, G-proteins, polymerases and other cellular processes and to treat cellular proliferative diseases.
Gray; Nathanael S. (Berkeley, CA), Schultz; Peter (Oakland, CA), Kim; Sung-Hou (Moraga, CA), Meijer; Laurent (Roscoff, FR)
The Regents of the University of California (Oakland, CA), Centre National de la Recherche (FR)
10/ 352,752
January 27, 2003
GOVERNMENT RIGHTS This invention was made with Government support under Grant (Contract) No. DE-AC03-76SF00098 awarded by the U.S. Department of Energy. The Government has certain rights in this invention.