The invention provides substantially pure tumor suppressor nucleic acid molecules and tumor suppressor polypeptides. The invention also provides hairpin ribozymes and antibodies selective for these tumor suppressor molecules. Also provided are methods of detecting a neoplastic cell in a sample using detectable agents specific for the tumor suppressor nucleic acids and polypeptides.
STATEMENT AS TO FEDERALLY-FUNDED RESEARCH
This invention was supported by government support under contract number DE-FG03-98ER62624 awarded by the United States Department of Energy. The government has certain rights in this invention.