Fluorescently marked targets bind to a substrate 230 synthesized with polymer sequences at known locations. The targets are detected by exposing selected regions of the substrate 230 to light from a light source 100 and detecting the photons from the light fluoresced therefrom, and repeating the steps of exposure and detection until the substrate 230 is completely examined. The resulting data can be used to determine binding affinity of the targets to specific polymer sequences.
GOVERNMENT RIGHTS NOTICE
This invention was made with Government support under grant nos. DE-FG03-92ER81275 (SBIR) awarded by Department of Energy and/or H600813-1, -2 between Affymetrix, Inc. and the National Institute of Health. The Government has certain rights in this invention.