Skip to Content
Find More Like This
Return to Search

Multiflavor streptavidin

United States Patent

April 9, 2002
View the Complete Patent at the US Patent & Trademark Office
Compounds and methods are described for producing streptavidin mutants with changed affinities. In particular, modifications to the sequence of the natural streptavidin gene is described to create amino acid substitutions resulting in greater affinity for biotin substitutes than for biotin.
Reznik; Gabriel O. (Boston, MA), Sano; Takeshi (Needham, MA), Vajda; Sandor (Medfield, MA), Smith; Cassandra (Boston, MA), Cantor; Charles (Del Mar, CA)
The Trustees of Boston University (Boston, MA)
09/ 381,430
March 23, 2000
This invention was made with government support under U.S. Department of Energy Grant No. DE-FG02-93ER61656. The Government of the United States of America has certain rights in the invention.