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Treatment of addiction to ethanol and addictive-related behavior

United States Patent

November 27, 2001
View the Complete Patent at the US Patent & Trademark Office
Brookhaven National Laboratory - Visit the Office of Technology Commercialization and Partnerships Website
The present invention provides a highly efficient method for treating alcohol addiction and for changing addiction-related behavior of a mammal suffering from alcohol addiction. The method includes administering to a mammal an effective amount of gamma vinylGABA or a pharmaceutically acceptable salt thereof. In one embodiment, the method of the present invention includes administering to the mammal an effective amount of a composition which increase central nervous system GABA levels wherein the effective amount is sufficient to diminish, inhibit or eliminate behavior associated with craving or use of alcohol.
Dewey; Stephen L. (Manorville, NY), Brodie; Jonathan D. (Cos Cob, CT), Ashby, Jr.; Charles R. (Miller Place, NY)
Brookhaven Science Associates (Upton, NY)
09/ 635,578
August 9, 2000
This invention was made with Government support under Contract NO. DE-ACO2-98CH10886, between the U.S. Department of Energy and Brookhaven Science Associates. The Government has certain rights in the invention.