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Nucleic acid-coupled colorimetric analyte detectors

United States Patent

October 23, 2001
View the Complete Patent at the US Patent & Trademark Office
Lawrence Berkeley National Laboratory - Visit the Technology Transfer and Intellectual Property Management Department Website
The present invention relates to methods and compositions for the direct detection of analytes and membrane conformational changes through the detection of color changes in biopolymeric materials. In particular, the present invention provide for the direct colorimetric detection of analytes using nucleic acid ligands at surfaces of polydiacetylene liposomes and related molecular layer systems.
Charych; Deborah H. (Albany, CA), Jonas; Ulrich (Mainz, DE)
Regents of the University of California (Oakland, CA)
09/ 337,973
June 21, 1999
This invention was made in part during work partially supported by the U.S. Department of Energy under DOE Contract No.: DE-AC03-76SF00098. The government has certain rights in the invention.