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Method for photo-altering a biological system to improve biological effect

United States Patent

6,095,147
August 1, 2000
View the Complete Patent at the US Patent & Trademark Office
Photodynamic therapy is a new adjunctive therapy for filtration surgery that does not use chemotherapy agents or radiation, but uses pharmacologically-active sensitizing compounds to produce a titratable, localized, transient, post operative avascular conjunctiva. A photosensitizing agent in a biological system is selectively activated by delivering the photosensitive agent to the biological system and laser activating only a spatially selected portion of the delivered photosensitive agent. The activated portion of the photosensitive agent reacts with the biological system to obtain a predetermined biological effect. As a result, an improved spatial disposition and effectuation of the biological effect by the photosensitive agent in the biological system is achieved.
Hill; Richard A. (Irvine, CA), Doiron; Daniel R. (Santa Ynez, CA), Crean; David H. (Santa Barbara, CA)
The Regents of the University of California (Oakland, CA)
08/ 347,956
December 1, 1994
This invention was made with Government support under Contract No. 44514322443 awarded by the Department of Energy. The Government has certain rights in this invention.