Skip to Content
Find More Like This
Return to Search

Process for the preparation of protected dihydroxypropyl trialkylammonium salts and derivatives thereof

United States Patent

6,084,131
July 4, 2000
View the Complete Patent at the US Patent & Trademark Office
A process for the preparation of protected dihydroxypropyl trialkylammonium salts, particularly in chiral form is described. In particular, a process for the preparation of (2,2-dimethyl-1,3-dioxolan-4-ylmethyl)trialkylammonium salts, particularly in chiral form is described. Furthermore, a process is described wherein the (2,2-dimethyl-1,3-dioxolan-4ylmethyl)trialkylammonium salts is a 2,2-dimethyl-1,3-dioxolan-4-ylmethyl trimethylammonium salt, preferably in chiral form. The protected dihydroxypropyl trialkylammonium salts lead to L-carnitine (9) when in chiral form (5).
Hollingsworth; Rawle I. (Haslett, MI), Wang; Guijun (East Lansing, MI)
Board of Trustees operating Michigan State University (East Lansing, MI)
09/ 321,220
May 27, 1999
STATEMENT REGARDING FEDERALLY SPONSORED RESEARCH OR DEVELOPMENT This invention was supported in part by a United States Department of Energy Grant No. DE-FG02-89ER14029. The U.S. government has certain rights in this invention.