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Method and apparatus for staining immobilized nucleic acids

United States Patent

6,056,859
May 2, 2000
View the Complete Patent at the US Patent & Trademark Office
Oak Ridge National Laboratory - Visit the Partnerships Directorate Website
A method for staining immobilized nucleic acids includes the steps of affixing DNA probes to a solid substrate, moving target DNA material into proximity with the DNA probes, whereby the target DNA hybridized with specific ones of the DNA probes, and moving a fluorescent dye into proximity with the hybridized target DNA, whereby the fluorescent dye binds to the hybridized DNA to enable subsequent detection of fluorescence.
Ramsey; J. Michael (Knoxville, TN), Foote; Robert S. (Oak Ridge, TN), Jacobson; Stephen C. (Knoxville, TN)
Lockheed Martin Energy Research Corporation (Oak Ridge, TN)
08/ 800,241
February 12, 1997
This invention was made with government support under Contract No. DE-AC05-840R21400 awarded by the U.S. Department of Energy to Lockheed Martin Energy Systems, Inc. and the government has certain rights in this invention.