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Hydroxymethyl phosphine compounds for use as diagnostic and therapeutic pharmaceuticals and method of making same

United States Patent

6,054,115
April 25, 2000
View the Complete Patent at the US Patent & Trademark Office
A compound and method of making a compound for use as a diagnostic or therapeutic pharmaceutical comprises at least one functionalized hydroxyalkyl phosphine donor group and one or more sulfur or nitrogen donor and a metal combined with the ligand.
Katti; Kattesh V. (Columbia, MO), Karra; Srinivasa Rao (Columbia, MO), Berning; Douglas E. (Columbia, MO), Smith; C. Jeffrey (Columbia, MO), Volkert; Wynn A. (Columbia, MO), Ketring; Alan R. (Columbia, MO)
The Curators of the University of Missouri (Columbia, MO)
09/ 033,928
March 3, 1998
GRANT REFERENCE The research carried out in connection with this invention was supported in part by a grant from the Department of Energy (DOE-DEFG0289ER60875). The Government has certain rights in the invention.