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Boron-containing amino carboxylic acid compounds and uses thereof

United States Patent

6,037,490
March 14, 2000
View the Complete Patent at the US Patent & Trademark Office
Novel compounds which are useful for boron neutron capture therapy (BNCT) are disclosed. The compounds comprise a stable boron-containing group and an aminocycloalkane carboxylic acid group or a boronated acyclic hydrocarbon-linked amino carboxylic acid. Methods for synthesis of the compounds and for use of the compounds in BNCT are disclosed.
Kabalka; George W. (Knoxville, TN), Srivastava; Rajiv R. (Knoxville, TN)
The University of Tennessee Research Corporation (Knoxville, TN)
08/ 923,054
September 3, 1997
This invention was developed in the course of work supported by the Department of Energy under Contract DE-FG05-93-ER 61610.