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Boron containing amino acid compounds and methods for their use

United States Patent

6,017,902
January 25, 2000
View the Complete Patent at the US Patent & Trademark Office
Brookhaven National Laboratory - Visit the Office of Technology Commercialization and Partnerships Website
The present invention provides new boron containing amino acid compounds and methods for making these compounds by contacting melphalan or another nitrogen mustard derivative and sodium borocaptate. The present invention also provides a method of treating a mammal having a tumor by administering to the mammal a therapeutically effective amount of the new boron containing amino acid compounds.
Glass; John D. (Shoreham, NY), Coderre; Jeffrey A. (Wading River, NY)
Brookhaven Science Associates (Upton, NY)
09/ 258,105
February 25, 1999
This invention was made with Government support under contract number DE-AC02-98CH10886, awarded by the U.S. Department of Energy. The Government has certain rights in the invention.