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Formulation for Tin-.sup.117m /diethylenetriaminepentaacetic acids

United States Patent

6,004,532
December 21, 1999
View the Complete Patent at the US Patent & Trademark Office
Brookhaven National Laboratory - Visit the Office of Technology Commercialization and Partnerships Website
The invention provides improved formulations of .sup.117m Sn (Sn.sup.4+) DTPA which allow higher doses of .sup.117m Sn (Sn.sup.4+) to be administered than were previously possible. Methods for making pharmaceutical compositions comprising .sup.117m Sn (Sn.sup.4+) DTPA in which the amount of unchelated DTPA is minimized are disclosed along with methods of using the improved formlulations, both for palliation of bone pain associated with cancer and for treatment of osseous tumors.
Srivastava; Suresh C. (Setauket, NY), Meinken; George E. (Middle Island, NY)
Brookhaven Science Associates (Upton, NY)
09/ 093,200
June 8, 1998
This invention was made with Government support under contract number DE-AC02-98CH 10886, awarded by the U.S. Department of Energy. The Government has certain rights in the invention.