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Laser vaporization/ionization interface for coupling microscale separation techniques with mass spectrometry

United States Patent

5,917,185
June 29, 1999
View the Complete Patent at the US Patent & Trademark Office
Ames Laboratory - Visit the Iowa State University Research Foundation - Office of Intellectual Property & Technology Transfer Website
The present invention provides a laser-induced vaporization and ionization interface for directly coupling microscale separation processes to a mass spectrometer. Vaporization and ionization of the separated analytes are facilitated by the addition of a light-absorbing component to the separation buffer or solvent.
Yeung; Edward S. (Ames, IA), Chang; Yu-chen (Taichung Hsien, TW)
Iowa State University Research Foundation, Inc. (Ames, IA)
08/ 882,855
June 26, 1997
STATEMENT OF GOVERNMENT RIGHTS This invention was made with government support under grants from the United States Department of Energy (Contract No. W-7405-Eng-82). The U.S. government has certain rights in this invention.