The present invention provides a laser-induced vaporization and ionization interface for directly coupling microscale separation processes to a mass spectrometer. Vaporization and ionization of the separated analytes are facilitated by the addition of a light-absorbing component to the separation buffer or solvent.
STATEMENT OF GOVERNMENT RIGHTS
This invention was made with government support under grants from the United States Department of Energy (Contract No. W-7405-Eng-82). The U.S. government has certain rights in this invention.