A digital imaging system and method using multiple cameras arranged and aligned to create a much larger virtual image sensor array. Each camera has a lens with an optical axis aligned parallel to the optical axes of the other camera lenses, and a digital image sensor array with one or more non-contiguous pixelated sensors. The non-contiguous sensor arrays are spatially arranged relative to their respective optical axes so that each sensor images a portion of a target region that is substantially different from other portions of the target region imaged by other sensors, and preferably overlaps adjacent portions imaged by the other sensors. In this manner, the portions imaged by one set of sensors completely fill the image gaps found between other portions imaged by other sets of sensors, so that a seamless mosaic image of the target region may be produced.
 The United States Government has rights in this invention pursuant to Contract No. W-7405-ENG48 between the United States Department of Energy and the University of California for the operation of Lawrence Livermore National Laboratory.