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In vivo unnatural amino acid expression in the methylotrophic yeast pichia pastoris

United States Patent Application

20090197339
A1
View the Complete Application at the US Patent & Trademark Office
The invention provides orthogonal translation systems for the production of polypeptides comprising unnatural amino acids in methylotrophic yeast such as Pichia pastoris. Methods for producing polypeptides comprising unnatural amino acids in methylotrophic yeast such as Pichia pastoris are also provided.
Young, Travis (San Diego, CA), Schultz, Peter G. (La Jolla, CA)
The Scripps Research Institute (La Jolla CA)
12/ 316,370
December 10, 2008
STATEMENT AS TO RIGHTS TO INVENTIONS MADE UNDER FEDERALLY SPONSORED RESEARCH AND DEVELOPMENT [0002] The invention was made with United States Government support under Grant No. DE-FG03-00ER46051 from the United States Department of Energy, Division of Materials Sciences. The United States Government has certain rights in the invention.