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Method of reducing peak broadening in analytical measurements

United States Patent Application

20090128812
A1
View the Complete Application at the US Patent & Trademark Office
Los Alamos National Laboratory - Visit the Technology Transfer Division Website
A method of reducing peak width in flow-through analytical instrumentation measurements, comprising introducing a sample into an analytical instrument; recording the time required for a plurality of individual analytes within the sample to travel a known distance between a first point and a second point within the analytical instrument to produce a plurality of travel times; recording the time required for a plurality of individual analytes within a sample to travel a known distance between a first point and a second point to produce a plurality of travel times; dividing the travel times into a plurality of groups comprising a fixed number of travel times; assigning a ranking to the travel times within a group; selecting from each group at least one travel time to produce a set of selected travel times; and producing from the set of selected travel times an output signal in the form of a peak.
Keller, Richard A. (Los Alamos, NM), Beveridge, Andrew Cameron (Los Alamos, NM), Yoshida, Thomas M. (Los Alamos, NM), Pratt, Lawrence Riley (Los Alamos, NM), Jett, James Hubert (Albuquerque, NM)
12/ 286,944
October 2, 2008
STATEMENT OF FEDERAL RIGHTS [0002] The United States government has rights in this invention pursuant to Contract No. DE-AC52-06NA25396 between the United States Department of Energy and Los Alamos National Security, LLC for the operation of Los Alamos National Laboratory.