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Characterizing exposure to ionizing radiation

United States Patent Application

20080076122
A1
View the Complete Application at the US Patent & Trademark Office
Lawrence Livermore National Laboratory - Visit the Industrial Partnerships Office Website
A method of characterizing exposure to ionizing radiation, utilizing the steps of selecting a set of biomarker geness for characterizing exposure to ionizing radiation, and using the set of biomarker genes for characterizing exposure to ionizing radiation. The step of selecting a set of biomarker genes for characterizing exposure to ionizing radiation was developed utilizing a unique set of 420 oligonucleotide probes for human genes capable of discerning past exposure to different doses of ionizing radiation. The step of selecting a set of biomarker genes for characterizing exposure to ionizing radiation utilizes groupings of genes that represent candidate panels of mRNA biomarkers.
Wyrobek, Andrew J. (Walnut Creek, CA), Coleman, Matthew A. (Oakland, CA), Nelson, David O. (Oakland, CA), Tucker, James (Novi, MI)
The Regents of the University of California
11/ 528,296
September 26, 2006
[0001] The United States Government has rights in this invention pursuant to Contract No. W-7405-ENG-48 between the United States Department of Energy and the University of California for the operation of Lawrence Livermore National Laboratory.