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Methods and systems of common motif and countermeasure discovery

United States Patent Application

20080059077
A1
View the Complete Application at the US Patent & Trademark Office
Lawrence Livermore National Laboratory - Visit the Industrial Partnerships Office Website
Disclosed are computational methods, and associated hardware and software products for identifying a set of target pockets for broad-spectrum drug development based on a provided set of protein motifs. A method of identifying the provided set protein motifs based on a plurality of protein motifs in also disclosed herein. Additional methods for generating a plurality of protein motifs based on both aligned protein structure and sequences are disclosed herein.
Zhou, Carol E. (Pleasanton, CA), Zemla, Adam T. (Brentwood, CA), Roe, Diana C. (Newark, CA), Schoeniger, Joseph P. (Oakland, CA)
The Regents of the University of California (1111 Franklin Street 12th Floor Oakland CA 94607-5200)
11/ 818,075
June 12, 2007
STATEMENT REGARDING FEDERALLY FUNDED RESEARCH [0002] The United States Government has rights in this invention pursuant to Contract No. W-7405-ENG-48 between the United States Department of Energy and the University of California, for the operation of Lawrence Livermore National Laboratory.