Skip to Content
Find More Like This
Return to Search

GENERATION OF MESOPOROUS MATERIALS USING MULTIPHASE SURFACTANT SYSTEMS

United States Patent Application

20180105430
A1
View the Complete Application at the US Patent & Trademark Office
Sandia National Laboratories - Visit the Intellectual Property Management and Licensing Website
The present invention relates to the discovery that mesoporous silica nanoparticles may be modified in pore size from the natural mesophase by generating mesoporous materials in binary, ternary or multiphase surfactant systems to produce biphasic, triphasic or multiphase mesoporous structures. Thus, the present invention relates to methods of producing biphase, triphasic and multiphase mesoporous structures with finely tuned mesopore size and protocells which are produced therefrom and mesoporous silica nanoparticles obtained therefrom. The resulting mesoporous nanostructures may be used to create protocells having unique cargo loading and release characteristics. Related protocells, pharmaceutical compositions and therapeutic and diagnostic methods are also provided.
Carnes, Eric C. (Albuquerque, NM), Brinker, C. jeffrey (Albuquerque, NM), Dunphy, Darren (Albuquerque, NM), Heisey, Trevin (Albuquerque, NM)
15/ 557,368
March 11, 2016
[0002] This invention was made with government support under DE-AC04-94AL85000 awarded by the Department of Energy. The government has certain rights in the invention.