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Methods for binding agents to b-amyloid plaques

United States Patent Application

20070053831
A1
View the Complete Application at the US Patent & Trademark Office
A method for labeling structures, such as .beta.-amyloid plaques and neurofibrillary tangles, in vivo or in vitro, is provided and comprises contacting brain tissue with one or more compounds, preferably radiolabeled for detection by positron emission tomography (PET).
Barrio, Jorge R. (Agoura Hills, CA), Petric, Andre J. (Ljubljana, SI), Satyamurthy, Nagichettiar (Los Angeles, CA), Kepe, Vladimir (Los Angeles, CA), Small, Gary W. (Los Angeles, CA)
10/ 557,655
May 20, 2004
ACKNOWLEDGMENT OF GOVERNMENT SUPPORT [0002] This invention was made with government support under Grant No. DE-FC0387-ER60615, awarded by the United States Department of Energy. The government has certain rights in the invention.