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QUANTITATIVE DETECTION OF PATHOGENS IN CENTRIFUGAL MICROFLUIDIC DISKS

United States Patent Application

20180037960
A1
View the Complete Application at the US Patent & Trademark Office
Sandia National Laboratories - Visit the Intellectual Property Management and Licensing Website
A system and methods for detection of a nucleic acid including forming a plurality of nucleic acid detection complexes are described, each of the complexes including a nucleic acid analyte, a detection agent and a functionalized probe. The method further including binding the nucleic acid detection complexes to a plurality of functionalized particles in a fluid sample and separating the functionalized particles having the nucleic acid detection complexes bound thereto from the fluid sample using a density media. The nucleic acid analyte is detected by detecting the detection agent.
Koh, Chung-Yan (Dublin, CA), Schaff, Ulrich Y. (Livermore, CA), Sommer, Gregory Jon (Maple Grove, MN)
15/ 788,492
October 19, 2017
GOVERNMENT RIGHTS [0002] This invention was made with Government support under Contract No. DE-AC04-94AL85000 awarded by the U.S. Department of Energy. The Government has certain rights in the invention.