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CHIMERIC ENZYMES FOR CONVERSION OF LIGNIN-DERIVED CHEMICALS

United States Patent Application

20180023061
A1
View the Complete Application at the US Patent & Trademark Office
National Renewable Energy Laboratory - Visit the NREL Technology Transfer Website
Disclosed herein are enzymes useful for the dealkylation of aromatic substrates, including the conversion of guaiacol or guaethol to catechol. Methods of converting aromatic substrates found in lignin-based feedstocks such as pyrolysis oil into products such as catechol are also disclosed. Also presented herein are methods for rapidly evolving and optimizing genetic regions.
NEIDLE, Ellen Lee (Dacula, GA), JOHNSON, Christopher W. (Denver, CO), BECKHAM, Gregg Tyler (Golden, CO), LINGER, Jeffrey G. (Denver, CO), EITEMAN, Mark Andrew (Athens, GA), TUMEN-VELASQUEZ, Melissa (Athens, GA), AHMED, Alaa Ashraf Mahmoud (Athens, GA)
15/ 658,789
July 25, 2017
CONTRACTUAL ORIGIN [0002] The United States Government has rights in this invention under Contract No. DE-AC36-08GO28308 between the United States Department of Energy and Alliance for Sustainable Energy, LLC, the Manager and Operator of the National Renewable Energy Laboratory.