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SULFUR-CONTAINING COMPOUNDS TARGETING VESICULAR ACETYLCHOLINE TRANSPORTER

United States Patent Application

20170355675
A1
View the Complete Application at the US Patent & Trademark Office
The present invention generally relates to various compounds that are useful as vesicular acetylcholine transporter (VAChT) ligands. The invention further relates to methods of using these compounds and their radiolabeled analogs for the detection of neurodegenerative diseases including Parkinson's disease (PD), and Alzheimer's disease (AD).
Tu, Zhude (St. Louis, MO), Luo, Zonghua (St. Louis, MO), Liu, Hui (St. Louis, MO), Jin, Hongjun (St. Louis, MO), Parsons, Stanley M. (Santa Barbara, CA)
Washington University (St. Louis MO), The Regents of the University of California (Oakland CA)
15/ 620,263
June 12, 2017
GOVERNMENT LICENSE RIGHTS [0002] This invention was made with Government support under Grant Numbers NS061025, NS075527, and MH092797 awarded by the National Institutes of Health and DE-SC0012737 awarded by the Department of Energy. The Government has certain rights in the invention.