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LANTHANIDE-CHELATOR COMBINATORIAL BARCODING

United States Patent Application

20170348665
A1
View the Complete Application at the US Patent & Trademark Office
Lawrence Berkeley National Laboratory - Visit the Technology Transfer and Intellectual Property Management Department Website
Disclosed herein are methods for tracking solutions, (e.g., reaction conditions in solutions). In some embodiments, the method comprises: contacting a first lanthanide-chelator complex to a first solution to generate a first barcoded solution, wherein the first lanthanide-chelator complex comprises a first lanthanide chelated by a first chelator; contacting a second lanthanide-chelator complex to a second solution to generate a second barcoded solution, wherein the second lanthanide-chelator complex comprises a second lanthanide chelated by a second chelator; mixing the first barcoded solution and the second barcoded solution to form one or more mixtures; and identifying the first lanthanide ions in the mass spectrum and the second lanthanide ions in the mass spectrum to track the condition of each of the one or more mixtures.
Duncombe, Todd (Oakland, CA), Northen, Trent R. (Walnut Creek, CA), Deng, Kai (Orinda, CA), Singh, Anup K. (Danville, CA)
15/ 611,662
June 1, 2017
STATEMENT REGARDING FEDERALLY SPONSORED R&D [0002] This invention was made with government support under grant no. DE-ACO2-05CH11231 awarded by the U.S. Department of Energy. The government has certain rights in the invention.