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ECTEINAMYCIN, COMPOSITIONS AND USES THEREOF

United States Patent Application

20170348278
A1
View the Complete Application at the US Patent & Trademark Office
An isolated or synthesized compound of Formula I and salts thereof are provided. A compound isolated from Actinomadura and having a chemical formula of C.sub.38H.sub.60O.sub.12 is also provided. Compositions including the compounds and methods of using the compounds to treat bacterial infections including gram positive infections such as C. difficile are also disclosed. ##STR00001##
BUGNI, Timothy Scott (Madison, WI), WYCHE, Thomas Philip (Chelsea, MA), BRAUN, Douglas R. (Mount Horeb, WI), PIOTROWSKI, Jeffrey S. (Madison, WI), SAFDAR, Nasia (Madison, WI)
15/ 522,713
October 28, 2015
STATEMENT OF GOVERNMENT SUPPORT [0002] This invention was made with government support under GM107557 and GM104192 awarded by the National Institutes of Health and DE-FCO2-07ER64494 awarded by the US Department of Energy. The government has certain rights in the invention.