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SYSTEMS AND METHODS FOR CONTINUOUSLY FERMENTING C5 AND C6 SACCHARIDES

United States Patent Application

20170342444
A1
View the Complete Application at the US Patent & Trademark Office
This invention provides optimized fermentation of cellulosic and hemicellulosic sugars. Biomass-derived hemicellulosic and cellulosic sugars are independently conditioned and separately fermented, utilizing reuse and recycle of microorganisms, metabolic intermediates, and nutrients. Conditioned sugars can be fermented in separate vessels, where excess cells from glucose fermentation are conveyed to hemicellulose sugar fermentation along with raffinate from solvent recovery, to enhance productivity and product yield. Some variations provide a method of fermenting C.sub.5 and C.sub.6 sugars to fermentation products, the method comprising: fermenting a C.sub.6-rich sugar feed to a first fermentation product; fermenting a C.sub.5-rich sugar feed to a second fermentation product; removing microorganism cells from the first fermentor, to maintain a cell concentration within a selected range; conveying microorganism cells to a second fermentor; and removing microorganism cells from the second fermentor, to maintain a microorganism cell concentration that is greater than that in the C.sub.6-rich fermentor.
SURVASE, Shrikant (Thomaston, GA), ZEBROSKI, Ryan (Fayetteville, GA), ADAMOS, Georgios (Thomaston, GA), PYLKKANEN, Vesa (Atlanta, GA)
15/ 605,930
May 25, 2017
STATEMENT OF GOVERNMENT RIGHTS [0002] This invention was made with government support under Contract No. DE-EE0006879 awarded by the United States Department of Energy, Office of Energy Efficiency & Renewable Energy. The U.S. government has certain rights in this invention.