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HIGH EFFICIENCY CONTINUOUS-FLOW PRODUCTION OF RADIOISOTOPES

United States Patent Application

20170337998
A1
View the Complete Application at the US Patent & Trademark Office
Methods and systems are provided for continuous-flow production of radioisotopes with high specific activity. Radioisotopes with high specific activity produced according to the methods described are also provided. The methods can include causing a liquid capture matrix to contact a target containing a target nuclide; irradiating the target with radiation, ionizing radiation, particles, or a combination thereof to produce the radionuclides that are ejected from the target and into the capture matrix; and causing the liquid capture matrix containing the radionuclides to flow from the target to recover the capture matrix containing the radionuclides with high specific activity. The methods are suitable for the production of a variety of radionuclides. For example, in some aspects the target nuclide is .sup.237Np, and the radionuclide is .sup.238Np that decays to produce .sup.238Pu. In other aspects, the target nuclide is .sup.98Mo, and the radionuclide is .sup.99Mo that decays to produce .sup.99mTc.
Nilsson, Mikael (Irvine, CA), Safavi-Tehrani, Leila (Ladera Ranch, CA), Miller, George E. (Irvine, CA)
15/ 598,918
May 18, 2017
STATEMENT REGARDING FEDERALLY SPONSORED RESEARCH OR DEVELOPMENT [0002] This invention was made with government support under award NRC-HQ-11-G-38-0037 awarded by the Nuclear Regulatory Commission and award DE-NE-0000361 awarded by the Department of Energy The government has certain rights in the invention.