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BIO-ASSESSMENT DEVICE AND METHOD OF MAKING THE DEVICE

United States Patent Application

20170307594
A1
View the Complete Application at the US Patent & Trademark Office
Los Alamos National Laboratory - Visit the Technology Transfer Division Website
Disclosed herein are embodiments of a device that can be used to mimic the biochemical and physiological actions of a lung organ. Also disclosed herein are embodiments of components that are included in the device as well as methods of making and using the device. Further disclosed are platform device embodiments and various components used therein that can be used in combination with the lung organ devices disclosed herein. In some embodiments, the disclosed devices can be used to determine drug toxicity and also can be used with one or more disease models to determine methods of treating disease.
Iyer, Rashi (Los Alamos, NM), Huang, Jen-Huang (Los Alamos, NM), Nath, Pulak (Los Alamos, NM), Harris, Jennifer (Los Alamos, NM)
Los Alamos National Security, LLC (Los Alamos NM)
15/ 513,949
September 24, 2015
ACKNOWLEDGMENT OF GOVERNMENT SUPPORT [0002] This invention was made with government support under Contract No. DE-AC52-06NA25396, awarded by the U.S. Department of Energy; and grant number R-00284-12-0, awarded by the Defense Threat Reduction Agency (DTRA). The government has certain rights in the invention.