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IMMUNOASSAYS FOR THE DIFFERENTIATION OF BACTERIAL PATHOGENS IN HUMAN SERUM

United States Patent Application

20170307604
A1
View the Complete Application at the US Patent & Trademark Office
Los Alamos National Laboratory - Visit the Technology Transfer Division Website
Systems for and methods of capturing, detecting, quantifying, and characterizing target moieties that are characterized by having a lipophilic portion of sufficient size and chemical composition whereby the target moiety inserts (or partitions) into a lipid assembly are described. Methods of diagnosing a subject as having a bacterial infection by detecting bacterial pathogen associated molecular pattern (PAMP) molecules in serum are further described.
Mukundan, Harshini (Los Alamos, NM), Kubicek-Sutherland, Jessica (Los Alamos, NM), Jakhar, Shailja (Los Alamos, NM), Noormohamed, Aneesa (Los Alamos, NM), Swanson, Basil I. (Los Alamos, NM), Sakamuri, Rama Murthy (Los Alamos, NM), Stromberg, Loreen (Los Alamos, NM)
Los Alamos National Security, LLC
15/ 640,865
July 3, 2017
ACKNOWLEDGMENT OF GOVERNMENT SUPPORT [0002] This invention was made with government support under Contract No. DE-AC52-06NA25396 awarded by the United States Department of Energy. The government has certain rights in the invention.