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MULTI-ORGAN MEDIA COMPOSITIONS AND METHODS OF THEIR USE

United States Patent Application

20170275587
A1
View the Complete Application at the US Patent & Trademark Office
Los Alamos National Laboratory - Visit the Technology Transfer Division Website
Disclosed herein are media for culture of cells, tissues, and/or organs. The media formulations disclosed herein can be used to support growth, viability, and/or function of one or more than one cell type, tissue, or organ. In some embodiments, one or more cell types, tissues, organ devices, and/or organs are contacted with a disclosed culture medium under conditions sufficient to support growth, viability, and/or function of the cell types, tissues, and/or organs. The disclosed media can be used in methods of culturing multiple cell types, and in some examples, is used in a platform device including one or more organ devices, for example, by circulating the medium through the one or more organ devices in the platform.
Iyer, Rashi (Los Alamos, NM), Harris, Jennifer F. (Los Alamos, NM), Huang, Jen-Huang (Los Alamos, NM), Nath, Pulak (Los Alamos, NM), Przekwas, Andrzej (Huntsville, AL)
15/ 513,948
September 24, 2015
ACKNOWLEDGMENT OF GOVERNMENT SUPPORT [0002] This invention was made with government support under Contract No. DE-AC52-06NA25396 awarded by the U.S. Department of Energy and grant number CMBXCEL-XLI-2-0001 awarded by the Defense Threat Reduction Agency (DTRA). The government has certain rights in the invention.