A system and methods for transporting light and then intensifying the light are provided. The system and methods can be utilized for a number of applications, including the detection and treatment of cancer and restenosis. Laser light is transported through a catheter (composed of capillaries) which can be fed into a patient allowing the end of the catheter to be placed in close proximity to a tumor. The laser light at the end of the catheter assembly can be reduced in pulse duration and focused to high intensity onto a target and thereby generate in vivo pulses of ionizing radiation.
STATEMENT CONCERNING FEDERALLY SPONSERED RESEARCH
 The development of this invention was in part supported by a government contract of the National Science Foundation grant number 0530778 and the Department of Energy grant number DEFG0205ER15663.