Skip to Content
Find More Like This
Return to Search

TRANSGENIC CELLS WITH INCREASED PLASTOQUINONE LEVELS AND METHODS OF USE

United States Patent Application

20170107530
A1
View the Complete Application at the US Patent & Trademark Office
Los Alamos National Laboratory - Visit the Technology Transfer Division Website
Disclosed herein are transgenic cells expressing a heterologous nucleic acid encoding a prephenate dehydrogenase (PDH) protein, a heterologous nucleic acid encoding a homogentisate solanesyl transferase (HST) protein, a heterologous nucleic acid encoding a deoxyxylulose phosphate synthase (DXS) protein, or a combination of two or more thereof. In particular examples, the disclosed transgenic cells have increased plastoquinone levels. Also disclosed are methods of increasing cell growth rates or production of biomass by cultivating transgenic cells expressing a heterologous nucleic acid encoding a PDH protein, a heterologous nucleic acid encoding an HST protein, a heterologous nucleic acid encoding a DXS protein, or a combination of two or more thereof under conditions sufficient to produce cell growth or biomass.
Sayre, Richard T. (Los Alamos, NM), Subramanian, Sowmya (Los Alamos, NM), Cahoon, Edgar (Lincoln, NE)
Los Alamos National Security, LLC (Los Alamos NM)
15/ 389,061
December 22, 2016
ACKNOWLEDGMENT OF GOVERNMENT SUPPORT [0002] This invention was made with government support under Contract No. DEAC52-06NA25396 awarded by the U.S. Department of Energy. The government has certain rights in the invention.