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Precise Microbiota Engineering at the Cellular Level

United States Patent Application

View the Complete Application at the US Patent & Trademark Office
Stably immunized cells and methods of making stably immunized cells are provided. Methods of altering the microbiota of an ecological environment are provided. Methods of modifying target chromosomes are provided. Methods of delivering genetic material to target cells are provided.
Esvelt, Kevin M. (Auburndale, MA), Yaung, Stephanie (San Jose, CA)
President and Fellows of Harvard College (Cambridge MA), President and Fellows of Harvard College (Cambridge MA)
15/ 034,682
November 5, 2014
STATEMENT OF GOVERNMENT INTERESTS [0002] This invention was made with government support under DE-FG02-02ER63445 awarded by Department of Energy and under N66001-12-C-4040 awarded by Defense Advanced Research Projects Agency. The government has certain rights in the invention.