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RECOMBINANT YEAST HAVING INCREASED TOLERANCE TO IONIC LIQUIDS AND METHODS OF USE

United States Patent Application

20160333362
A1
View the Complete Application at the US Patent & Trademark Office
The present invention relates to materials and methods for the production of ethanol. More particularly, the present invention provides genetically modified strains of Saccharomyces cerevisiae having enhanced tolerance for ionic liquid (IL) toxicity. Also provided are methods of using such genetically engineered yeast strains for improved IL-mediated hydrolysis of lignocellulosic biomass for industrial-scale production of various fuels, chemical feedstocks, and synthetic polymers.
Piotrowski, Jeff Scott (Madison, WI), Bottoms, Scott (Madison, WI), Dickinson, Quinn (Madison, WI), Landick, Robert Chase (Madison, WI)
15/ 154,537
May 13, 2016
STATEMENT REGARDING FEDERALLY SPONSORED RESEARCH OR DEVELOPMENT [0002] This invention was made with government support under DE-FC02-07ER64494 awarded by the US Department of Energy. The government has certain rights in the invention.