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PROMOTER SEQUENCE OF 3-PHOSPHOGLYCERATE KINASE GENE 1 OF LACTIC ACID -PRODUCING FUNGUS RHIZOPUS ORYZAE AND A METHOD OF EXPRESSING A GENE OF INTEREST IN FUNGAL SPECIES

United States Patent Application

*** PATENT GRANTED ***
20020102636
6,465,635
A1
View the Complete Application at the US Patent & Trademark Office
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The present invention provides the promoter clone discovery of phosphoglycerate kinase gene 1 of a lactic acid-producing filamentous fungal strain, Rhizopus oryzae. The isolated promoter can constitutively regulate gene expression under various carbohydrate conditions. In addition, the present invention also provides a design of an integration vector for the transformation of a foreign gene in Rhizopus oryzae.
GAO, Johnway (Richland, WA), Skeen, Rodney S. (Pendleton, OR)
09/ 536,034
March 27, 2000
[0001] This invention was made with Government support under Contract DE-AC0676RL01830 awarded by the U.S. Department of Energy. The Government has certain rights in the invention.