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METHODS OF TREATING PARKINSON'S DISEASE USING VIRAL VECTORS

United States Patent Application

20160256534
A1
View the Complete Application at the US Patent & Trademark Office
Lawrence Berkeley National Laboratory - Visit the Technology Transfer and Intellectual Property Management Department Website
Methods of delivering viral vectors, particularly recombinant adeno-associated virus (rAAV) virions, to the central nervous system (CNS) using convection enhanced delivery (CED) are provided. The rAAV virions include a nucleic acid sequence encoding a therapeutic polypeptide. The methods can be used for treating CNS disorders such as for treating Parkinson's Disease.
Bankiewicz, Krystof (Garrett Park, MD), Cunningham, Janet (Alameda, CA)
Genzyme Corporation (Framingham MA), The Regents of the University of California (Oakland CA)
15/ 081,116
March 25, 2016
REFERENCE TO GOVERNMENT RIGHTS [0002] Part of this work was made under the auspices of the U.S. Department of Energy, at the University of California/Lawrence Berkeley National Laboratory, under CRADA No. BG98039 and DOE Contract No. DE-AC03-76SF00098, now Contract No. DE-AC02-05CH11231. The government has certain rights in this invention.