Skip to Content
Find More Like This
Return to Search

SYSTEMS AND METHODS FOR DETERMINING FLUX DISTRIBUTION

United States Patent Application

20160232278
A1
View the Complete Application at the US Patent & Trademark Office
Provided are systems and methods for accurately determining flux distribution in organisms or cells without use of metabolic flux analysis data. The methods include estimating flux distributions in multiple reference strains (variants of a parental strain) using experimentally determined extracellular flux data from the reference strains, and determining a flux distribution for the parental strain from the estimated flux distributions for the reference strains and from experimentally measured extracellular fluxes for the parental strain. The systems are configured for carrying out the methods.
Reed, Jennifer Leanne (Madison, WI), Long, Matthew Ray (Madison, WI)
WISCONSIN ALUMNI RESEARCH FOUNDATION (Madison WI)
15/ 015,561
February 4, 2016
STATEMENT REGARDING FEDERALLY SPONSORED RESEARCH [0001] This invention was made with government support under DE-SC0008103 awarded by the US Department of Energy. The government has certain rights in the invention.