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United States Patent Application

View the Complete Application at the US Patent & Trademark Office
Sandia National Laboratories - Visit the Intellectual Property Management and Licensing Website
Provided herein are mutant asparaginase enzymes that lack glutaminase activity. Also provided are methods of treating ASNS-negative cancer cells with a glutaminase-free asparaginase.
REMPE, Susan (Albuquerque, NM), ROGERS, David M. (Tampa, FL), ANISHKIN, Andriy (Austin, TX), SUKHAREV, Sergei (Bethesda, MD), LORENZI, Philip L. (Pearland, TX), CHAN, Wai Kin (Houston, TX), WEINSTEIN, John N. (Bellaire, TX)
14/ 917,934
September 10, 2014
[0002] The invention was made with government support under Grant No. DE-AC04-94AL85000 awarded by the Department of Energy. The government has certain rights in the invention.