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United States Patent Application

View the Complete Application at the US Patent & Trademark Office
In various embodiments, a device may generally comprise a remote ablation chamber comprising an inlet and an outlet, a laser to deposit energy into a sample in the chamber to ablate the sample and generate ablation products in the chamber, a transport device in fluid communication with the outlet, an ionization source to ionize the ablation products to produce ions, and a mass spectrometer having an ion transfer inlet to capture the ions. The ablation products or the ions may be transported in a fluid stream from the ablation chamber through the transport device. The distance from the outlet of the ablation chamber to the ion transfer inlet may be from 1 cm to 10 m. Methods of making and using the same are also described.
Vertes, Akos (Reston, VA), Compton, Laine (Springfield, VA), Powell, Matthew (Westover, WV), Reschke, Brent (Morgantown, WV), Friend, Jordan (Morgantown, WV)
Protea Biosciences, Inc. (Morgantown WV), The George Washington University (Washington DC)
14/ 912,506
August 26, 2014
STATEMENT OF GOVERNMENTAL INTEREST [0001] This invention was made with Government support under Grant No. 0719232 awarded by the National Science Foundation and Grant No. DEFG02-01ER15129 awarded by the U.S. Department of Energy. The government has certain rights in the invention.