Provided are microorganisms that catalyze the synthesis of chemicals and biochemicals from a methanol, methane and/or formaldehyde. Also provided are methods of generating such organisms and methods of synthesizing chemicals and biochemicals using such organisms.
STATEMENT REGARDING FEDERALLY SPONSORED RESEARCH
 This invention was made with Government support under DE-AR0000430, awarded by the U.S. Department of Energy Advanced Research Projects Agency, and 0963183, awarded by the National Science Foundation. The Government has certain rights in the invention.